Dizygotic Twins with Down Syndrome Complicating Pregnancy - A Unique Case

Scientific evaluation of current bibliography depicts the significance of prenatal diagnosis in terms of proper gestations surveillance.

Appearance of such chromosomal anomalies is strongly accompanied with mother age, previous obstetrical or gynecologic history, previous surgical procedures.

Ultrasound depiction of Nuchal Translucency (NT) reflects the tendency of such gestations to develop such anomalies, influencing further pregnancy course.

Final diagnosis, in cases of increased NT, consists Chorionic Villus Sampling (CVS) and further karyotype evaluation.
Among prenatal appearance of chromosomal anomalies, Trisomy 21 or Down syndrome represents the most common type with characteristic morphologic and clinical diagnosis.

Prenatal diagnosis of dizygotic twins of opposite sex type with simultaneous appearance of Down Syndrome is very rare throughout current literature.

Our study reflects presentation of such unique and rare case with proper diagnosis and treatment.

Keywords: Trisomy 21, Down Syndrome, Nuchal Translucency, Chorionic Villus Sampling.